Fig. 5
From: Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders
All models achieve high performance in the SRPBS sample. The ROC curves and the AUC show the performance of each model for healthy controls and MDD patients. In healthy controls the accuracies were 75%, 73.3%, and 74.1% for the limbic, non-limbic and whole brain model, respectively. When accounting for eTIV the accuracy and the AUC decreased in all models, yielding 65.2%, 69.2% and 70.3% accuracy for limbic (eTIV), non-limbic (eTIV) and whole brain (eTIV), respectively. For the MDD group the accuracies were slightly lower for all models (raw models: 71.9%, 69.9% and 70.7%; eTIV-corrected: 63.5%, 64.7%, 68.3% for limbic, non-limbic and whole brain, respectively)