Fig. 6
From: Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
CD99 blockade inhibits proliferation in human T cells. Anti-CD3 and anti-CD28 stimulated cryopreserved T cells from 27 healthy controls (n = 12 females and n = 15 males) were treated with anti-CD99 mAb (clone HCD99) or the respective isotype control antibody and proliferation was tracked by cluster formation in the IncuCyte® for 7 days. Data are shown as mean ± SEM. Statistics: Wilcoxon matched-pairs signed rank test; *P < 0.05; **P < 0.01; ***P < 0.001