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Fig. 7 | Biology of Sex Differences

Fig. 7

From: Gene regulatory networks reveal sex difference in lung adenocarcinoma

Fig. 7

Sex difference in transcription factor targeting of genes commonly targeted by drugs in lung cancer in TCGA and validation data GSE68465, split by smoking status. The heatmap shows t-statistics corresponding to the sex coefficient from a limma analysis on the gene targeting score (indegree) (p-value < 0.05 for the sex coefficient). Genes with higher targeting in male samples are marked in blue and genes with higher targeting in female samples are marked in red

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