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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Human-specific protein-coding and lncRNA genes cast sex-biased genes in the brain and their relationships with brain diseases

Fig. 3

Consensus coexpression modules of period- and region-specific genes. The colors with numbers indicate modules and gene numbers. (A) Modules of period-specific genes and enriched GO terms. Each module shows period-specific enrichment for sex-biased genes. For example, turquoise_1679 is enriched for sex-biased genes only in fetuses (FDR = 3.0E-56, OR = 6.32), and purple_337, cyan_175, pink_442, tan_229, brown_840, and lightcyan_153 are enriched for sex-biased genes in adulthood (FDR = 4.02E14, 0.0005, 2.71E44, 2.99E69, 2.93E168, 2.54E50, OR = 2.39, 1.78, 4.17, 15.11, 8.36, 18.01). This feature is reflected by links between periods and modules. (B) Modules of region-specific genes and the enriched GO terms

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Biology of Sex Differences

ISSN: 2042-6410

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