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Fig. 4 | Biology of Sex Differences

Fig. 4

From: Human-specific protein-coding and lncRNA genes cast sex-biased genes in the brain and their relationships with brain diseases

Fig. 4

Conserved and species-specific sex-biased genes in human and macaque brains. (A) The numbers of conserved and species-specific sex-biased lncRNA genes in 14 brain regions in adolescence and adulthood. (B) The four pairs of color bars indicate the enrichment of the four GO terms in humans and macaques. Each dot in these bars indicates a sex-biased gene set that is enriched for subterms of the GO term (with the position of the dot on the Y axis indicating the number of enriched subterms). The lines between the dots in the two bars link the corresponding sex-biased gene sets. (C) The percentage of conserved and species-specific lncRNA genes involved in “neurogenesis”. (D) Genes in humans but not in macaques are enriched for immune-related GO terms. Shown are “driver terms in GO”

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