Fig. 1

Comparable adiposity develops at different timepoints in male and female mice. A Experimental setup (created with BioRender). B Bodyweight (gram) was measured weekly from the start of the diet (week 0) until the time of sacrifice (arrows, AS1-3). Male mice gained weight earlier on HFD than female mice. As seen by the SEM, weight gain also varied less between male mice than within female mice. p ≤ 0.05*. C, D Relative vAT and scAT weight at sacrifice. (n = 6/♂ AS1 HFD, AS3 HFD, ♀ AS1 HFD, LFD, AS3 LFD; n = 5/♂ AS1 LFD, AS2 HFD, LFD, AS3 LFD, ♀ AS2 HFD, LFD, AS3 HFD); p ≤ 0.05*, p ≤ 0.005**, p ≤ 0.001***, p ≤ 0.0001****