Fig. 7

Testosterone-dependent changes in activity and temperature in CJL males. (A) Actograms of locomotor activity and body temperature rhythms under control or chronic jet lag (CJL) conditions in castrated mice with vehicle-implantation (V) or testosterone-implantation (T). (B) Chi-square periodogram based on body temperature rhythms under light-dark cycles (LD, control or CJL conditions) or following constant darkness (DD). The blue line is the significance level (p = 0.001). (C–F) The circadian period (C, E) and rhythm robustness (D, F) of activity and temperature rhythms in castrated mice with vehicle-implantation (V) or testosterone-implantation (T) under control or CJL conditions (C, D) or following DD (E, F), based on chi-square periodogram. Data are presented as means ± standard errors of the means (S.E.M). Two-way ANOVA followed by Šidák’s multiple comparison test, ** p < 0.01, *** p < 0.001, **** p < 0.0001