Fig. 6

Effects of H. pylori infection on gut microbiota in mice of different genders after 4 months. Alpha diversity of gut microbiome, as indicated by Chao (A) and Shannon (B) indices. The Relative abundance of the dominant phyla (C) and genera (D). E PCoA of the fecal samples from mice with and without infection. LEfSe analysis of discriminant genera of gut microbiome between males and females with (G) and without (F) infection. n = 4–8/group. N represented the number of samples. *, p < 0.05. F_Con_F_4M, fecal samples from females without infection at 4 months. F_Hp_F_4M, fecal samples from females following 4 months infection. M_Con_F_4M, fecal samples from males without infection at 4 months. M_Hp_F_4M, fecal samples from males following 4 months infection