Fig. 8

Increased anxiety-like behavior in female wild-type (WT-Kmo^+/+) offspring from HET-Kmo^+/– parents. A Distance traveled in the elevated zero maze (Two-way RM ANOVA Genotype effect F_{(1, 70)} = 44.25, ^^^^P < 0.0001 with Fisher’s LSD post hoc test ***P < 0.001, ****P < 0.0001). B Entries to open and closed area in the elevated zero maze (Females: Two-way RM ANOVA Genotype effect F_{(1, 64)} = 14.71, ^^^P < 0.001 with Fisher’s LSD post hoc test *P < 0.05, **P < 0.01). C Number of grooming events in the sucrose splash test (Two-way RM ANOVA Sex effect F_{(1, 65)} = 4.093, ^P < 0.05). D Latency to grooming in the sucrose splash test. Data are mean ± SEM. N = 11–24 per group