Fig. 9

Female wild-type (WT-Kmo^+/+) from HET-Kmo^+/– parents have reduced NREM sleep and more wake in comparison to wild-type (WT-Control) mice during the light phase. A Total NREM duration (Females: Two-way RM ANOVA Genotype effect F_{(1, 10)} = 4.776, P = 0.054). B Total wake duration (Females: Two-way RM ANOVA Genotype effect F_{(1, 10)} = 5.584, ^P < 0.05). C NREM sleep spectral power (Females: Two-way RM ANOVA Genotype effect F_{(1, 10)} = 8.711, ^P < 0.05, Genotype × Frequency interaction F_{(38, 380)} = 2.022, ^^^P < 0.001). D REM sleep spectral power (Females: Two-way RM ANOVA Genotype × Frequency interaction F_{(38, 380)} = 1.487, ^P < 0.05). E Relative cage activity (Unpaired t test: *P < 0.05). Data are mean ± SEM. N = 6–10 per group